Gibberellins (GA) and abscisic acid (ABA) are two phytohormones that regulate, in an antagonistic way, plant growth as well as several developmental processes from seed maturation and germination to flowering time, through hypocotyl elongation and root growth. In general, ABA and GA inhibit and promote, respectively, cell elongation and growth. Consequently, this mutual antagonism between GA and ABA governs many developmental decisions in plants.In addition to its role as a growth and development modulator, ABA is primarily known for being a major player in the response and adaptation of plants to diverse abiotic stress conditions, including cold, heat, drought, salinity or flooding. Remarkably, different works have also recently pointed to a function for GA in the control of some biological processes in response to stress.The selection of research and review papers of this book, mostly focused on ABA, covers a wide range of topics related to the most recent advances in the molecular mechanisms of ABA and GA functions in plants.

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A combination of dry lab bioinformatic analyses and wet lab molecular experiments seems to be a major trend for biological studies. The authors of the papers included in this reprint tried to elucidate the linkage between environmental stress and molecular response, and the species investigated in each of the articles are phylogenetically and agriculturally diverse. These exemplar studies will potentially ignite more ideas and biological stories to investigate gene functions.

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This collection of 25 research papers comprised of 22 original articles and 3 reviews is brought together from international leaders in bioinformatics and biostatistics. The collection highlights recent computational advances that improve the ability to analyze highly complex data sets to identify factors critical to cancer biology. Novel deep learning algorithms represent an emerging and highly valuable approach for collecting, characterizing and predicting clinical outcomes data. The collection highlights several of these approaches that are likely to become the foundation of research and clinical practice in the future. In fact, many of these technologies reveal new insights about basic cancer mechanisms by integrating data sets and structures that were previously immiscible.

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As key decomposers within ecosystems, edible fungi embody the principles of circular agricultural production which emphasize reduction, reuse, and recycling. The realization of this sustainable approach to agriculture is inextricably linked to the cutting-edge biotechnology pertaining to edible fungi. This collection reports recent advancements and compiles reviews concerning the development of edible fungi biotechnology, offering readers an enhanced comprehension of the unique characteristics that set fungi apart from plants and animals.

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Viruses exhibit an elegant simplicity as they are so basic, but so frightening. Although only a few are life threatening, they have substantial implications for human health and the economy, as exemplified by the ongoing coronavirus pandemic. Viruses are rather small infectious agents found in all types of life forms, from animals and plants to prokaryotes and archaebacteria. They are obligate intracellular parasites, and as such, subvert many molecular and cellular processes of the host cell to ensure their own replication, amplification, and subsequent spread. This Special Issue addresses the cell biology of viral infections based on a collection of original research articles, communications, opinions, and reviews on various aspects of virus–host cell interactions. Together, these articles not only provide a glance into the latest research on the cell biology of viral infections but also include novel technological developments.

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Dilated cardiomyopathy (DCM) is a particular phenotype of non-ischemic systolic heart failure, frequently recognizing a genetic background and affecting relatively young patients with few comorbidities. Nowadays, long-term survival of DCM patients has been markedly improved due to an early diagnosis and uninterrupted and tailored follow-up under constant optimal medical and non-pharmacological evidence-based treatments. Nevertheless, DCM is still one of the most common causes of heart transplantation in the western world. Clinical management requires an integrated and systematic use of diagnostic tools and a deeper investigation of the basic mechanisms underlying the disease. However, several emerging issues remain debated. Specifically, the genotype–phenotype correlation, the role of advanced imaging techniques and genetic testing, the lack of appropriate risk stratification models, the need for a multiparametric and multidisciplinary approach for device implantation, and a continuous reclassification of the disease during follow-up remain challenging issues in clinical practice. Therefore, the aim of this Special Issue is to shed the light on the most recent advancements in characterization and clinical management of DCM in order to unveil the conundrum of this particular disease.

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In this Special Issue, authors from nine countries on five continents provide overviews on and insights into current research topics related to the ‘Genetic Complexity of Hormone-Sensitive Cancers’. The chapters cover topics on completely novel technologies and instruments revolutionizing our view of biological entities, and also, novel extensions and revisions of existing and well-established technologies such as genetic probes and bar-coding techniques, which add a new dimension to microscopy, as they allow us to visualize DNA sequences and mRNA in situ. With this Special Issue, the editors wanted to create a forum for the international biomedical research community to compile their data on the genetic complexity of cancer in a unique resource. While this collection of articles cannot certainly claim completeness in any way, it represents an attractive collection of the different aspects of hormone-dependent cancers and will hopefully encourage further targeted research.

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In recent years, heavy metals have been widely used in agricultural, chemical, domestic, and technological applications, causing environmental and soil contaminations. Heavy metals enter the plant system through soil or via the atmosphere, and can accumulate, affecting physiological processes, plant growth, yield, and human health if heavy metals are stored in edible tissues. Understanding the regulation mechanisms of plant heavy metals accumulation and partitioning is important to improve the safety of the food chain. In this Special Issue book, a total of 19 articles were included; four reviews covering phytoremediation, manganese phytotoxicity in plants, the effect of cadmium on plant development, the genetic characteristics of Cd accumulation, and the research status of genes and QTLs in rice, respectively, as well as fifteen original research articles, mainly regarding the impact of cadmium on plants. Cadmium was therefore the predominant topic of this Special Issue, increasing the attention of the research community on the negative impacts determined by cadmium or cadmium associated with other heavy metals. The articles have highlighted a great genetic variability, suggesting different possibilities for accumulation, translocation and the reduction or control of heavy metal toxicity in plants.

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This reprint presents 13 papers published in the Special Issue entitled "Molecular Research for Cereal Grain Quality" of the International Journal of Molecular Sciences, together with an editorial. All of these papers provide new scientific insights into molecular research for cereal grain quality, with most studies focusing on the grain quality of rice and wheat crops. More papers with a broader coverage of the grain quality features of different cereal crops need to be collected in future Special Issues.

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In this Special Issue, we present the state of the art in the field of pig genetics and genomics, including the identification of gene candidates linked to important pig traits and to nutritional modifications, with the aim of collecting the most recent advances. The published manuscripts focused on high-throughput methodologies, such as RNA sequencing, ATAC-seq, MACE-seq, chip-seq, and RRBS, and covered other fields of pig genetics. The pig (Sus scrofa) is the most common large mammal in the world. The Sus genus includes domestic pig and wild boar. Since the draft reference genome sequence of S. scrofa was assembled in 2012, the processes of identification of genes related to important phenotypic traits and of search of genetic markers for pig selection have been significantly refined. In addition, the newest wide-range high-throughput techniques, including microarrays, next-generation sequencing, and the recent PacBio sequencing platform providing ultra-long sequencing reads, allow identifying gene mutations and gene candidates throughout the whole genome, transcriptome, or epigenome and estimating quantitative traits important for breeding as well as the genetic backgrounds of inherited diseases.

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This Special Issue contains 28 papers covering a wide range of topics related to plant genomics and genetics. The papers utilize a variety of genomic tools and techniques to explore topics such as identification of quantitative trait loci associated with flax seed yield and oil quality, mucilage and hull content in flax seeds, and genomic prediction for pasmo resistance in flax. Other papers focus on the identification and characterization of specific genes, such as the EXO70 gene family in wheat and related species, hydroxycinnamoyl transferase in tea plants, and the WRKY transcription factor GmWRKY12 in soybeans. Several papers examine gene expression and regulation in response to abiotic stress, such as drought and salt tolerance in moso bamboo, and the response to chilling in bell peppers. Other topics include genetic diversity analysis of crested wheatgrass, genome-wide analysis of chitin-binding protein gene family in peppers, and genome-wide bioinformatics analysis of MAPK gene family in kiwifruit. Overall, this Special Issue provides a comprehensive view of the current state of plant genomics research, showcasing the diversity of approaches and tools being used to better understand and improve crop plants.

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Vols 1 and 2 contain 57 papers in the Special Issue of ‘Plant Genomics 2009’ and cover a wide range of topics, highlighting the significant progress that has been made in recent years in our understanding of the genetics and genomics of plants’ growth, development, and stress responses. These studies provide valuable insights into the potential applications of genomic tools and technologies for crop improvement and sustainable agriculture, as well as fundamental questions about the evolution and function of plant genes and genomes.

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Vols 1 and 2 contain 57 papers in the Special Issue of ‘Plant Genomics 2009’ and cover a wide range of topics, highlighting the significant progress that has been made in recent years in our understanding of the genetics and genomics of plants’ growth, development, and stress responses. These studies provide valuable insights into the potential applications of genomic tools and technologies for crop improvement and sustainable agriculture, as well as fundamental questions about the evolution and function of plant genes and genomes.

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Integrative omics of plants in response to stress conditions play more crucial roles in the post-genomic era. High-quality genomic data provide more deeper understanding of how plants to survive under environmental stresses. This book is focused on concluding the recent progress in the Protein and Proteome Atlas in plants under different stresses. It covers various aspects of plant protein ranging from agricultural proteomics, structure and function of proteins, and approaches for protein identification and quantification.

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

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This book is a collection of eight articles, of which seven are reviews and one is a research paper, that together form a Special Issue that describes the roles that long noncoding RNAs (lncRNA) play in gene regulation at a post-transcriptional level.

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Consumers and stakeholders are increasingly demanding that the meat industry guarantees high-quality meat products with stable and acceptable sensory and safety properties. To do this, it is necessary to understand the mechanisms that underlie the conversion of muscle into meat, as well as the impact of pre- and post-harvest procedures on the final quality and safety of meat products. Over the last two decades, sophisticated OMICs technologies—genomics, transcriptomics, proteomics, peptidomics, metabolomics and lipidomics, also known as foodomics—have been powerful approaches that extended the scope of traditional methods and have established impressive possibilities of addressing meat quality issues. Foodomics were further used to elucidate the biological basis/mechanisms of phenotypic variation in the technological and sensory quality traits of meat from different species. Overall, these techniques aimed to comprehensively study the dynamic link(s) between the genome and the quality traits of the meat that we eat compared to traditional methods, hence improving both the accuracy and sensitivity thanks to the large quantities of data that can be generated. This Special Issue focused on the cutting-edge research applications of OMICs tools to characterize or manage the quality of muscle foods. The research papers applied transcriptomics, targeted and untargeted proteomics, metabolomics, and genomics, among others, to evaluate meat quality, determine the molecular profiles of meat and meat products, discover and/or evaluate biomarkers of meat quality traits, and to characterize the safety, adulteration, and authenticity of meat and meat products.

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